Swisse

The Swisse formulae are based on over 25 years of research and backed by clinical studies, scientific validation or other evidence based on traditional use.

Harris, E., Kirk, J., Rowsell, R., Vitetta, L., Sali, A., Scholey, A.B., Papingas, A. 2011. The effect of multivitamin supplementation on mood and stress in healthy older men. Human Psychopharmacology: Clinical and Experimental, [published online].

Swisse Men’s Ultivite 50+ Ultivite study shows daily supplementation for eight weeks may help to boost alertness, mood and feelings of general wellbeing.

Study background:

This study was a randomised, double blind, placebo controlled trial involving 50 healthy male volunteers aged 50-69.  The men were supplemented for 8 weeks with a daily Swisse Men’s Ultivite 50+, containing a comprehensive range of vitamins, minerals, herbs and antioxidants, or alternatively a placebo.

The objective of the study was to investigate further the link between poor mood and a deficiency in several micronutrients.  Multivitamins contain a wide range of range of nutrients that may be beneficial in improving mood.  Until now, few randomised controlled trials have investigated this.

Data was collected via a series of mood and stress questionnaires at baseline and post-supplementation.  This data was assessed according to the Depression, Anxiety and Stress Scale (DASS).

Key findings:

• Significant improvements in alertness
• Compared with placebo, there was a significant reduction in the overall score on a depression anxiety and stress scale and an improvement in alertness and general daily functioning in the multivitamin group.

Conclusion:

• Supplementation with a multivitamin, mineral and herbal formulation may be useful in improving alertness and reducing negative mood symptoms and may also improve feelings of general day-to-day well-being

Macpherson, H.,  Ellis, K.A. Sali, A. & Pipingas, A. 2011. Memory improvements in elderly women following 16 weeks treatment with a combined multivitamin, mineral and herbal supplements A randomized controlled trial, Psychopharmacology, Online, 18 October 2011.

Swisse Women’s Ultivite 50+ study shows significant improvement in working memory, increased vitamin B12 levels, increased vitamin B6 levels, and reduced homocysteine levels.

Key findings:

Working memory: the study demonstrated that 16 weeks supplementation with Swisse Women’s Ultivite 50+ improved speed of spatial working memory response in community dwelling elderly women. Several other indicators of cognitive function were increased in the group that received supplementation, but these did not reach the level of statistical significance.

Vitamin B12: significantly increased in the group who received supplementation.

Vitamin B6: significantly increased in the group who received supplementation.

Homocysteine: levels were significantly decreased. Homocysteine is a marker of cardiovascular health.

Vitamin E: there was a noticeable trend to increased vitamin E levels in the treated group, although this trend did not reach clinically significant levels.

Safety: there were no significant effects of Swisse Women’s Ultivite 50+ supplementation on electrolytes, urea or liver function tests.

This is the first report of its kind with an Australian multivitamin supplement.

Study Aim and Design

The aim of this study was to investigate the effects of supplementation with Swisse Women’s Ultivite 50+ on cognitive and biochemical effects in a group of older women aged 64 – 82 years. The study was a double-blind, randomised, placebo-controlled study of 56 female participants, evenly split into control group and study group. Subjects were studied over a period of 16 weeks, carried out at Swinburne University of Technology: Brain Sciences Institute.

Study carried out by Swinburne University of Technology: Brain Sciences Institute:

Study title: Effects of Swisse Men’s Ultivite on cognition, mood, quality of life and blood measures in a group of older males.

Aim: To investigate the effects of supplementation with Swisse Mens Ultivite on cognition, mood, quality of life and blood measures in a group of older males.

Design: Double blind, randomized, placebo controlled study of 60 male participants, evenly split into control group and study group. Subjects were studied over a period of eight weeks.

Conclusions:

Cognition: Swisse Mens Ultivite improved performance accuracy on a contextual memory task; an effect not present in the placebo group. We have previously shown that performance on this task is susceptible to decline with increasing age. Swisse Mens Ultivite may therefore be effective in countering age related cognitive decline.

Mood: Swisse Mens Ultivite reduced clinical symptoms as measured by the Depression, Anxiety and Stress Scale (DASS). It appears the reductions in the DASS score overall was mainly due to the reduction of depressive symptoms and possibly also due to the reduction of symptoms of stress.

Health-Related Quality of Life: Swisse Mens Ultivite may be effective in improving health-related quality of life: A non-significant trend towards improvement in health-related quality of life, as measured by the General Health Questionnaire (GHQ) was found in the multivitamin group but not in the placebo group.

Blood tests: Swisse Mens Ultivite was effective in reducing homocysteine and increasing blood levels of vitamin B12 and folate:

* A statistically significant decrease (-12.5%) in homocysteine was found in the multivitamin group but not in the placebo group.
* A statistically significant increase (+26.6%) in vitamin B12 was found in the multivitamin group but not in the placebo group.
* A statistically significant increase (+25.5%) in red cell folate was found in the multivitamin group but not in the placebo group.

Study was carried out by Southern Cross University, with the Australian Centre for Complementary Medicine.

Study title: The Effect of a Nutritional Supplement on Premenstrual Syndrome

Aim: To investigate the effects of supplementation with Swisse Womens Ultivite on Premenstrual Symptoms utilizing the Premenstrual Symptom Score (PMSS) assessed by questionnaire as the primary outcome measure.

Design: Double blind, randomized, placebo controlled trial conducted over 42 weeks using parallel groups of individuals with prospectively confirmed mild to moderate premenstrual tension. The study included 49 subjects randomly allocated into 28 in the active group and 21 in the placebo group.

Psychological symptoms of PMS include depression, anxiety, anger and irritability, rapid mood swings, disinterest in normal activities and lack of concentration; food cravings and fatigue are common complaints while the physical discomforts, bloating, breast tenderness, abdominal pain and headache frequently occur. There were significant reductions in premenstrual syndrome symptoms between the pre-treatment and post treatment stages of the study. The reduction for the active treatment was highly significant and greater than the reduction in symptoms for subjects on placebo. The study showed a 50% improvement for subjects taking the active treatment.